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Research & Development

Translating Science Into Highly Innovative, Life-changing Medicines

For more than 240 years, Takeda has focused on bringing better health and a brighter future to people around the world by translating science into life-transforming medicines. Today, we are a top global biopharmaceutical innovator powered by approximately 50,000 people who come to work every day asking themselves the same question: How can we do more for patients?

With over 4,500 people focused in R&D, we do more for patients by translating science into highly innovative, life-transforming medicines across our core Therapeutic Areas in Innovative Biopharma: Oncology, Neuroscience and Gastrointestinal & Inflammation. We have a singular focus on diseases affecting patient groups with the most urgent needs and for whom treatments do not exist or are not good enough.

Innovative Biopharma Focus Areas

Oncology

For nearly two and a half centuries, Takeda’s mission has been improving people's health. In oncology, we have built upon that heritage, developing and delivering transformative treatments for patients with hematologic and solid cancers. We’ve structured our organization to ensure a tight connection from research to development to commercialization — enabling us to rapidly bring transformative medicines to market and meet the needs of the cancer community.

We keep the patient at the heart of everything we do. Our team works with agility, collaboration and scientific rigor, and our day-to-day connections are marked by trust, respect and honesty. To succeed here, it takes a sense of urgency, because we know that what we do, today and tomorrow, has the power to change lives — and even save them.

Learn more about Takeda Oncology

Neuroscience

Neuroscience is poised to reach a significant inflection point over the coming decade, and our team will be in the middle of it all, answering the call to transform treatment paradigms — or even create new ones. Whether we’re making advancements in understanding disease pathophysiology or pursuing new modalities that unlock previously undruggable targets, we’ll continue to push forward in providing more and more effective treatments for patients.

To deliver on our ambition, we’re applying our expertise in disease biology understanding, translational tools, and clinical development. We are investing in multiple modalities in parallel that could solve biodistribution challenges and unlock full efficacy for patients. At Takeda, we are driven by science and innovation, and aspire to be a trusted leader and partner in neuroscience.

Gastrointestinal and Inflammation

With over 30 years of experience in gastroenterology and a strategy to expand on our core expertise in inflammation, we are developing treatments in areas of high unmet need including inflammatory bowel disease, celiac disease, psoriasis, advanced liver disease, and neurogastric disorders.

To make a real difference, we must understand how GI and inflammatory diseases impact the everyday lives of patients. Routines are interrupted, symptom management takes precedence, and embarrassment can make the emotional pain just as present as the physical. Our approach is a simple one: we work where the needs of patients intersect with promising science.

Together with researchers, patient groups and other partners, we are working to advance scientific research and clinical medicine to improve disease management for all those affected by GI and inflammatory diseases.

The Leaders Shaping What's Next

Takeda Oncology’s vision is to develop life-saving medicines as rapidly as possible. Our multi-disciplinary team works to conquer tumor biology and deliver treatments that will transform the lives of cancer patients who inspire us each and every day.

P.K. Morrow
– Global Head, Oncology Therapeutic Area Unit
P.K. Morrow, Global Head, Oncology Therapeutic Area Unit

At Takeda, we are firmly committed to changing the treatment landscape for patients living with devastating neurological and neuromuscular diseases. We are focusing on diseases defined by genetics and metabolic pathways and are led by an inclusive, team-based approach with science and innovation at the core of everything we do.

Sarah Sheikh
– Head, Neuroscience Therapeutic Area Unit
Jane Doe, Role Type

With programs built on scientific evidence, in-house expertise, and global collaborations, we’re focused on delivering transformative therapies to improve the lives of patients living with gastrointestinal and hepatobiliary diseases.

Chinwe Ukomadu
– Head, Gastrointestinal and Inflammation Therapeutic Area Unit
Chinwe Ukomadu, Head, Gastrointestinal and Inflammation Therapeutic Area Unit

Takeda strives to deliver life-transforming therapies to as many patients as possible. Working with our network of world-class partners, our team is boldly advancing unprecedented mechanisms in our pipeline, working toward success for cancer patients worldwide.

Christopher Arendt,
– Ph.D., Chief Scientific Officer
Christopher Arendt, Ph.D., Chief Scientific Officer

Strategic investment areas

We are investing in platform capabilities in data sciences, as well as collaborating with academia and emerging biotech companies to tackle some of the most challenging problems in drug discovery and development. We are committed to our people and their growth and development. We know they are our most valuable asset and the driving force behind the innovation we strive to advance for patients.

There has never been a more exciting time to be part of R&D as we work to deliver breakthroughs to patients. We hope you will join us.

Where science is

A diverse & dynamic pipeline

We discover, develop and deliver life-transforming medicines for rare and more prevalent diseases across our focused therapeutic areas.

Core modalities with industry-leading expertise

  • Peptides & oligonucleotides

  • Microbiome & other modalities

  • Biologics

  • Small molecules

  • Externally-oriented mindset

    We seek innovation and partner to nurture it, wherever it resides.

  • ~100

    public-private partnerships across 76 countries

  • 200+

    active collaborations in place globally

  • Takeda clinical trials

    Takeda's commitment to transparency reflects our strong support for sharing clinical trial information to benefit patients and to foster scientific discovery in a way that maintains patient privacy and preserves the integrity of our research. Learn more at:

    Clinicaltrials.takeda.com

    Our talent

    Where Science is Foundational

    Where Science is Transformative

    Key locations

    • Boston, Massachusetts, USA
    • Zurich, Switzerland
    • Vienna, Austria
    • Shanghai, China
    • Shonan, Japan
    • Osaka, Japan
    • Singapore

    Our awards

    Top Science Employer 2020
    Scrip Awards Pharma Company of the Year 2019

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    Research & Development Careers at Takeda

    Takeda Research & Development is advancing a focused pipeline across OncologyNeuroscience and Gastrointestinal & Inflammation, powered by deep scientific expertise and a commitment to patients.

    Bringing together scientists, clinicians, data experts and drug development professionals, we combine patient-first sciencecutting-edge technology and global collaboration to transform promising discoveries into life-changing medicines.

    View Open R&D Roles

    Our Therapeutic Areas

  • Oncology

    We advance innovative therapies across hematologic, thoracic and gastrointestinal cancers through biologics, antibody-drug conjugates (ADCs) and immuno-oncology approaches.

  • Neuroscience

    We are advancing orexin science and other innovative approaches to better understand disease biology and help transform treatment for neurological and sleep-wake disorders.

  • Gastrointestinal & Inflammation

    Developing innovative therapies for immune-mediated diseases with a focus on addressing chronic inflammation and improving outcomes across multiple conditions.

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    Our Locations

    Takeda R&D operates as a connected global organization, bringing together scientific, clinical and technical expertise across major research and development hubs worldwide. From discovery through development, our teams collaborate across geographies to advance innovative medicines for patients.

    Cambridge, MA

    Home to Takeda's global R&D leadership and the majority of its research and development teams, Cambridge is where scientific strategy, discovery and development come together. Teams collaborate across therapeutic areas and functions to advance innovative medicines for patients worldwide.

    Shonan & Tokyo, Japan

    Rooted in Takeda's scientific heritage, Shonan and Tokyo unite world-class research and development expertise. These teams play a critical role in advancing breakthrough science across Takeda's global pipeline.

    Łódź, Poland

    As a key hub in Takeda's evolving global R&D network, Łódź is attracting specialized talent and building new capabilities that help shape the future of how we discover, develop and deliver medicines for patients worldwide.

    Our Core Modalities

    Our scientists advance innovative medicines through three core modalities, combining deep scientific expertise with a patient-focused approach to address serious diseases.

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