Takeda Co-op Program: Biotherapeutics Process Development Co-op – Downstream Purification (January -June)

Takeda's Biotherapeutics Process Development focuses on creating and optimizing the manufacturing processes for innovative biologic medicines, including monoclonal antibodies and other therapeutic proteins. BPD includescell line development, upstream cell culture, downstream purification, in-process analytics, pilot labs to facilitate scale up and transfer, and technology development teams, working collaboratively to deliver Takeda’s novel therapeutics. 

The co-op will support theproject through execution of typical purification operations, such as capture and polishing chromatography, depth filtration, tangential-flow filtration (TFF), etc., as well as bioconjugation, using high-throughput screening techniques under supervision. The co-op will participate in experimental design, purification experiments, data analysis, and communicating results to the broader BPD team. Additionally, the co-op will have the opportunity to collaborate with other teams from BPD and Analytical Development (AD). This opportunity will provide the student with relevant experience in both purification and bioconjugation process of biotherapeutics and facilitate development of key skills needed to thrive in the pharmaceutical industry.

How You Will Contribute:

As a Downstream Purification Co-op you will have the opportunity to…

• Keep complete records of experimental design, results, and conclusions with an electronic notebook.

• Share key results & findings through oral presentations and written reports.

• Complete other lab activities as needed.

Co-op Development Opportunities:

• Obtain Hands-on experiences of process development laboratory focusing on purification and bioconjugation process development

• Accumulate in-depth knowledge on development of biotherapeutics in different modalities, such as monoclonal antibodies, antibody-drug conjugates, etc.

• Work as part of Takeda’s Biotherapeutics Process Development Team for a period of approximately 6 months gaining hands-on experience with various aspects of process development

• Generate, analyze, and communicate results to Takeda scientists and engineers
  

Job Requirements:

• This position will be Fully Onsite (4+ days/week in office) out of the Takeda Lexingtonlocation

• Must be pursuing aBachelors/Masters/Ph.D.Degree in chemical engineering, biochemistry, biomedical engineering, chemistry, biotechnology, or related field. 

• Excellent communication skills, both oral and written

• Ability to learn new techniques and perform multiple tasks simultaneously

• Previous experience in a laboratory setting is required.

• Previous experience with purification setup, such as chromatography systems (AKTA), TFF, or high-throughput system/robotics in a laboratory setting is preferred.

• General knowledge of protein engineering, bioprocessing and bioconjugation is a plus.