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Director, R&D Efficiency Program & Change Management

Cambridge, Massachusetts
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  • Job Level: Senior
  • Travel: Minimal (if any)

Takeda has been translating science into breakthrough medicines for 240 years. Every step of the way, our teams have worked together to tackle some of the most challenging problems in drug discovery and development. Today, we’re a driving force behind innovative therapies that make a lasting difference to millions of patients around the world.

In R&D, all of our history and potential comes together in an environment that welcomes diversity of thought and amplifies every voice. Working closely with colleagues, you’ll play a key role in bringing our rich pipeline of products forward to help patients. Come join a team that’s earned trust for more than two centuries, and find out how advancing transformative therapies at Takeda will shape your bright future.

Job ID R0160944 Date posted 08/15/2025 Location Cambridge, Massachusetts

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Job Description

Are you looking for a patient-focused, innovation-driven company that will inspire you and empower you to shine? Join us as a Director, R&D Efficiency Program & Change Management in our Cambridge, MA office.

At Takeda, we are transforming the pharmaceutical industry through our R&D-driven market leadership and being a values-led company. To do this, we empower our people to realize their potential through life-changing work. Certified as a Global Top Employer, we offer stimulating careers, encourage innovation, and strive for excellence in everything we do. We foster an inclusive, collaborative workplace, in which our global teams are united by an unwavering commitment to deliver Better Health and a Brighter Future to people around the world.

Here, you will be a vital contributor to our inspiring, bold mission.

POSITION OBJECTIVES:

The R&D Global Portfolio Strategy function is responsible for powering better R&D pipeline decision-making. As Director, R&D Efficiency Program & Change Management, you will oversee the execution of the R&D Efficiency Program through robust program and change management capabilities.

This role is responsible for:

  • Designing, implementing, and operationalizing multi-year efficiency initiatives that enhance R&D processes, productivity, and value creation.  
  • Align cross-functional stakeholders, execute the change management capability build strategy, and build organizational adaptability.
  • Drive scalable frameworks for adoption and sustain long-term impact.
  • Ensure milestone tracking, resource optimization, risk mitigation, and the seamless integration of the Matae change management platform across R&D business rhythms.  
  • Managing vendor partnerships, overseeing reporting and governance, and driving strategic guidance to ensure on-time and high-quality delivery.

This role is critical in leading transformation within R&D, directly contributing to Takeda's growth, innovation, and long-term sustainability.  

POSITION ACCOUNTABILITIES:

  • Support execution and continuous improvement of the R&D Efficiency Program and the Change Management Capability Build Strategy and Governance Framework.  
  • Drive and support multi-year, high-impact initiatives to improve R&D efficiency, foster innovation, and enable cost savings.  
  • Partner with functional leaders and Efficiency Program leadership to oversee and execute program planning, progress tracking, risk management, resource allocation, workshops, and milestone achievement.  
  • Coordinate cross-functional rollout of efficiency and change management practices with change leaders and key stakeholders.  
  • Lead the development and delivery of change management training, ensuring integration of the Matae change management platform into business processes to support program adoption.  
  • Monitor and report key metrics, including program objectives, change management outcomes, and efficiency milestones, to identify continuous improvement opportunities.  
  • Allocate budget/resources effectively to support program success and capability building.  
  • Manage third-party vendors and service providers to ensure alignment with program standards and delivery expectations.  
  • Serve as a strategic advisor to leaders on the integration of program management, change adoption, and sustainability frameworks.  
  • Collaborate with the Center of Excellence Lead and Change Leader Coalition to ensure alignment with program goals with organizational strategies. 
  • Conduct regular assessments of efficiency and change management progress, ensuring data accuracy and alignment with R&D efficiency objectives.  
  • Stay informed on emerging trends in R&D efficiency, change management, and program execution to bring innovative practices into the organization.  
  • Support preparation of materials and presentations for governance bodies (RMC, TET, BOD), providing updates and securing alignment on program priorities.  
  • Work closely with the R&D Center of Business Excellence to communicate and highlight achievements in R&D Efficiency and Change Management Capability Build.  
  • Build and maintain key relationships across a broad sphere of influence, both internally and externally, to drive alignment and ensure program success. 

EDUCATION, BEHAVIORAL COMPETENCIES AND SKILLS:

Education:

  • 10 years related experience in pharmaceutical industry, with expertise in strategy, R&D operations, with business and financial acumen  
  • 5+ years experience in change management, organizational development & program implementation  
  • Advanced degree (MBA, or equivalent) preferred 

Competencies and Skills: 

  • Comprehensive understanding of the pharmaceutical industry  
  • Deep understanding of organizational change management methodologies and applications in pharmaceutical/R&D contexts 
  • Familiarity with change management platforms and tools, including analytics and reporting features  
  • Enterprise level leadership with the ability to inspire, motivate and drive results 
  • Excellent communicator, able to persuasively convey both ideas and data, verbally and in writing 
  • Proven skills as an effective team player who can engender credibility and confidence within and outside the company 
  • Executive leadership presence and confidence 
  • Demonstrated ability to influence and align diverse stakeholders across a matrixed global organization 
  • Experience managing high-impact programs and cross-functional teams 
  • Ability to make highly complex decisions that impact the enterprise 
  • Ability to seek diverse input from multiple constituents and stakeholders to drive innovative solutions 
  • Responsible for independently managing change strategy execution and related decisions across the R&D organization 
  • Expected to evaluate vendor performance and platform adoption risks and recommend solutions 
  • Effectively navigates the changing external and internal environment and leads others through change by creating and inspiring and engaging workplace 
  • Frequent engagement with Change Leaders, CoE (Center of Excellence) leadership, and senior R&D/Takeda enterprise stakeholders 
  • Comfortable challenging the status quo and bringing forward innovative solutions 
  • Visionary and forward thinking with the ability to influence and effectively drive organizational change and continuous innovation 
  • Ability to work in a global ecosystem (internal and external) with a high degree of complexity 
  • Role operates in a global, complex, and regulated environment, requiring flexibility and cross-functional coordination 

This position is currently classified as “ hybrid” in accordance with Takeda’s Hybrid and Remote Work policy.

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Takeda Compensation and Benefits Summary

We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices.

For Location:

USA - MA - Cambridge

U.S. Base Salary Range:

$174,500.00 - $274,230.00

The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job.The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location.

U.S. based employees may be eligible for short-term and/or long-termincentives. U.S.based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S.based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation.

EEO Statement

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.

Locations

USA - MA - Cambridge

Worker Type

Employee

Worker Sub-Type

Regular

Time Type

Full time

Job Exempt

Yes

It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.
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During my 20-year journey here, I’ve been fully supported by my colleagues, and I can’t say enough about our rich internal talent and the long-standing values that drive our decisions as we work to develop important medicines for the patients we serve.

Doug Coffman - Head, R&D Asset Transition & Integration Office, R&D Regional & Business Operations

When making any type of decision, the first thing we ask is 'how will this impact patients?’ Ultimately, we’re laser focused on the best interests of the patient, and I truly believe we follow through on that.

Meredith Culp - VP, Head of Neuroscience Therapeutic Area Strategy & Operations and Head of Global Development Integration Office

Our culture and shared values make us like a family here at Takeda. It doesn't feel like work when you're doing something you love with people you love, and when your outcome is really fantastic.

Alison Handley, Head, Center for External Innovation

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What we believe in

Our values of Takeda-ism are Integrity, Fairness, Honesty and Perseverance, with Integrity as the core. These are brought to life through actions based on Patient, Trust, Reputation and Business, in that order.

Our belief in putting people first extends beyond our patients — it includes their families and communities, as well as our Takeda colleagues and their families.

We are committed to embracing our differences, valuing different perspectives, and fostering a culture of respect, inclusiveness and empowerment.

Our embedded Diversity, Equity & Inclusion (DE&I) strategy enables us to attract and retain exceptional talent, drives innovation, and helps address systemic inequalities in our communities.

  • Integrity

  • Fairness

  • Honesty

  • Perseverance

Working at Takeda

  • Inclusion

    Here, you will feel welcomed, respected, and valued as a vital contributor to our global team.
  • Collaboration

    A strong, borderless team, we strive together towards our priorities and inspiring mission.
  • Innovation

    Bold initiatives, continuous improvement, and creativity are at the heart of how we bring scientific breakthroughs from the lab to patients.
  • Top Workplace

    Recognized for our culture and way of working, we’re one of only 17 companies to receive Top Global Employer® status for 2024.
  • Work-Life

    Our people-first mission extends beyond patients to include their families, communities, and our own Takeda family.
  • Empowerment

    Through trust and respect, you will have genuine support from leaders, managers, and colleagues to do your best work.

We're Steadfast In Our Commitment to Four Key Imperatives

Patient


Responsibly translate science into highly innovative medicines and accelerate access to improve lives worldwide.

People


Create an exceptional people experience.

Planet


Protect our planet.

Data & Digital


Transform Takeda into the most trusted, data-driven, outcomes-based biopharmaceutical company.

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About our location

Cambridge, Massachusetts


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